Acrylic acids and derivatives
Medchemexpress LLC KW-2478 | 819812-04-9 | >98.0% | C30H42N2O9 | 10MG
A potent small-molecule inhibitor of heat shock protein 90 (Hsp90) with a reported IC50 of approximately 3.8 nM. It demonstrates antitumor activity in hematological cancer models and has been evaluated in early-phase clinical studies for B-cell malignancies. Provided as a crystalline solid for research use.
- Potent Hsp90 inhibition (IC50 ≈ 3.8 nM).
- Demonstrated antitumor activity against hematological tumor cells.
- Evaluated in preclinical and early-phase clinical studies.
- High reported purity suitable for research (≥98%).
- Supplied as a crystalline solid for laboratory use.
- Intended for research use only, not for human or veterinary use.
Medchemexpress LLC HY-N1362 25mg , Salvianolic acid B Dan Shen Suan B;Lithospermic acid B CAS:121521-90-2 Purity:98%
Medchemexpress, HY-N1362 25mg Salvianolic acid B Dan Shen Suan B;Lithospermic acid B CAS:121521-90-2 Formula:C36H30O16 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0591 5mg Medchemexpress, Dehydrocostus Lactone CAS:477-43-0 Purity:>98%
Medchemexpress, HY-N0591 5mg Dehydrocostus Lactone CAS:477-43-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0901A 5mg Medchemexpress, Corynoxine B CAS:17391-18-3 Purity:>98%
Medchemexpress, HY-N0901A 5mg Corynoxine B CAS:17391-18-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0918 5mg Medchemexpress, Desmethoxyyangonin CAS:15345-89-8 Purity:>98%
Medchemexpress, HY-N0918 5mg Desmethoxyyangonin CAS:15345-89-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC YK11 10mg | 1370003-76-1 | 10MG
YK11 is a partial agonist of androgen receptor with osteogenic activity
Medchemexpress LLC HY-114304 10mg Medchemexpress, COH000 CAS:1534358-79-6 Purity:>98%
Medchemexpress, HY-114304 10mg COH000 CAS:1534358-79-6 COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-14586 5mg Medchemexpress, Irosustat CAS:288628-05-7 Purity:>98%
Medchemexpress, HY-14586 5mg Irosustat CAS:288628-05-7 Irosustat is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC KW-2478 819812-04-9 10mg
KW-2478 (CAS 819812-04-9) is a potent non-ansamycin inhibitor of heat shock protein 90 (Hsp90) Unlike traditional Hsp90 inhibitors such as 17-AAG KW-2478 exhibits improved aqueous solubility and reduced hepatotoxicity In multiple myeloma cell models KW-2478 induces degradation of Hsp90 client proteins and leads to downregulation of IgH translocation products including FGFR3 c-Maf and cyclin D1 thereby inhibiting cell proliferation and promoting apoptosis Additionally KW-2478 reduces levels of Cdk9 and phosphorylated 4E-BP1 further suppressing oncogenic transcriptional regulators This compound is a valuable tool for studying Hsp90-mediated pathways and evaluating therapeutic strategies in hematological malignancies
Medchemexpress LLC HY-12243 5mg Medchemexpress, CID-797718 CAS:370586-05-3 Purity:>98%
Medchemexpress, HY-12243 5mg CID-797718 CAS:370586-05-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Hydroxypropyl Cellulose S4115-50mg
Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility it is used as food additive and sieving matrix for DNA separations
American Radiolabeled Chemicals Inc NITRENDIPINE 3H 25UC
Nitrendipine-5-methyl-3H 25uCi in ethanol, 1 mCi/ml, 70-87 Ci/mmol, M.W. 360.3, Shipped in Dry Ice
Medchemexpress LLC (+)-Kavain | 500-64-1 | 99.1% | 5 MG
(+)-Kavain is a primary kavalactone derived from Piper methysticum, known for its anticonvulsive properties. It functions by interacting with voltage-dependent Na+ and Ca2+ channels, thereby attenuating vascular smooth muscle contraction. Additionally, it has been shown to bind to the α4β2δ GABAA receptor, enhancing GABA efficacy. Its anti-inflammatory actions have been extensively researched, making it a subject of study for inflammatory disease treatments.
- Attenuates vascular smooth muscle contraction by interacting with voltage-dependent Na+ and Ca2+ channels.
- Potentiates GABAA receptors by binding to the α4β2δ subtype.
- Exhibits anti-inflammatory effects.
Medchemexpress LLC Cycloartenyl ferulate | 21238-33-5 | MFCD01311686 | 99.0% | 602.89 | C40H58O4 | 5MG
Cycloartenyl ferulate is a triterpenoid ferulate research compound characterized for immunomodulatory and antitumor effects in vitro and in vivo. The compound is provided as a small-molecule reagent in milligram pack sizes and is soluble in DMSO under recommended handling conditions. It has a molecular weight of 602.89 g/mol and a molecular formula of C40H58O4.
Selleck Chemical LLC Oleandrin
Oleandrin (PBI-05204 Foliandrin Neriolin Neriostene Folinerin Corrigen Neriol) is an inhibitor of Na /K -ATPase with IC50 of 0 62 M Oleandrin induces apoptosis and reduces migration of human glioma cells in vitro